Kritika Rehani

  Everyone experiences random aches in their body. When an injury occurs, pain signals travel from the injured area up to your brain. Pain will usually subside rigorously because the injury heals. With chronic pain, your body continues to send pain signals to your brain, even after an injury heals. This will last numerous weeks to years. Chronic pain  is described as pain that lasts a minimum of 12 weeks. The pain may feel sharp or dull, causing a burning sensation within the affected areas. Chronic Pain Sign & Symptoms Chronic pain impacts your physical health, your emotions, and even your social life over time. The pain can cause other symptoms, like anxiety, depression, poor sleep, exhaustion, annoyance, guilt, loss of interest in sex, and so on. Chronic Pain Treatment Options Acknowledging chronic pain could also be a problem, but it is the first step towards treatment. Start consulting your doctor about chronic pain symptoms. It'll be easy to identify the source of the pai

  Cluster Headache (CH) Overview Cluster Headache is a major headache and is very common in a group of head problems called trigeminal autonomic cephalalgias. The term cluster headache comes from the fact that the attack occurred in groups, or “clusters.” During the group cycle, severe headaches also occur between 1─8 times a day. Cluster cycles can last for weeks or months and are usually terminated during periods of remission, or periods of headaches. It usually occurs at the age of 20-40 and this condition is more common in men than women. It contains a headache on one side of the head. It is related to symptoms that occur on the same side of the head where the pain persists, runny or crooked nose, including red or clear eye, and spraying or sweating of the face. Cluster Headache Causes ●     The exact cause of cluster heads is unknown, but cluster patterns suggest that abnormalities in the body's hypothalamus play a role. ●     Unlike migraine and tension headache, cluster head

  What is Phenylketonuria? Phenylketonuria  is a rare genetic condition that causes an amino alkanoic acid called phenylalanine to create within the body. Phenylalanine is found altogether in proteins and a few artificial sweeteners. Phenylalanine hydroxylase is an enzyme your body uses to convert phenylalanine into tyrosine, which your body must create neurotransmitters like epinephrine, norepinephrine, and dopamine.  Phenylketonuria  is caused by a defect within the gene that helps create phenylalanine hydroxylase. Phenylketonuria Sign & Symptoms Newborns with Phenylketonuria initially don't have any symptoms. However, without treatment, babies usually develop signs of Phenylketonuria within a few months. Phenylketonuria signs and symptoms  can be mild and may include: ●     A musty odor in the breath, skin, or urine ●     Neurological problems ●     Eczema ●     Microcephaly ●     Hyperactivity ●     Intellectual disability ●     Delayed development ●     Psychiatric disorde

  Rare NRG1 Fusion NRG1 (Neuregulin 1)  gene fusions are possibly actionable oncogenic drivers existing in some solid tumors. These end in the activation of ErbB2-/ErbB3-mediated signaling pathways and should perform as an oncogenic driver. Rare NRG1 Fusion Diagnosis and Treatment NRG1- fusion  proteins and genes in solid tumors are often recognized with the support of several procedures like immunohistochemistry and fluorescence in place hybridization, DNA next-generation sequencing, and targeted gene fusion panels on RNA. However, RNA sequencing remains the cornerstone of the detection of NRG1 gene fusions due to higher sensibility for genetic rearrangements than DNA-based methods, which generally don't cover the massive introns in NRG1. Rare NRG1 Fusion Treatment Options ●        Current/Off-label therapies ●        Chemo immunotherapy ●        Novel anti–PD-1 or anti–PD-L1 Agents ●        Monoclonal antibodies (mAbs) ●        And others. However, the available  Rare NRG1 Fusion

Traumatic Brain Injury is defined as a penetrating head injury that disrupts the normal functioning of the brain. It may result when the head suddenly hits an object or when an object pierces the skull and enters brain tissue. Got queries? Click here and get more insights @ Traumatic Brain Injury Market Landscape Traumatic Brain Injury Sign and Symptoms Signs and symptoms may appear directly, within 24 hours, or they'll emerge days or weeks after the injury. Sometimes the symptoms are subtle. An individual may notice a drag but not relate it to the injury. Some people will appear to possess no signs after a TBI, but their condition worsens later. Symptoms modify greatly depending on the severity of the head injury. They'll include any of the following: ●        Headache ●        Paralysis ●        Dilated pupils ●        Vision changes (blurred vision or seeing double) ●        Breathing problems ●        Inappropriate emotional responses ●        Difficult