Kritika Rehani

The Importance of Pharma Business Consulting Pharmaceutical business consulting has brought a plethora of beneficial modifications in the healthcare field. The majority of the healthcare companies can avoid pitfalls that may pull down their business downwards since they can get the necessary advice that will direct them in the right path. There is a slew of companies that have a forte in pharmaceutical business consulting like DelveInsight, BMGI India, L.E.K. Consulting, IQVIA and many others. They assist pharmaceutical companies to be able to enhance innovation and clinical differentiation; this is where a company can realize its full potential and innovation capabilities that can increase their investments. They also get an opportunity to be able to build portfolios and get to relate with investors, who can provide them with more productive product development that can work well with the consumer. When one deals with pharmaceutical business consulting, one also get a

Nonalcoholic fatty liverdisease (NAFLD) is a disease which is a result of the accumulation of excess fat in the liver in people who drink little to no alcohol. There exist two types of NAFLD, one being simple fatty liver and the other one being Nonalcoholic Steatohepatitis (NASH). Simple fatty liver, aka nonalcoholic fatty liver (NAFL), is a condition in which fat deposition is in the liver without any noticeable inflammation of liver cells. On the other hand, in case of NASH there is severe inflammation and damage of the liver cell, along with the excess of in the liver. It can lead to fibrosis, scarring, cirrhosis of the liver, and in serious cases liver cancer. The NAFLD incidence is progressivelycommon worldwide, especially in Western nations. It is the most common form of chronic liver disease, affecting about one-quarter of the population. Most people with NAFLD have simple fatty liver. Only a small number of people with NAFLD have NASH. Experts esti

What is Rare disease? A  rare disease  is a disease that affects a tiny percentage of the population. In other words, an  orphan disease  is a rare disease, which means that there is a shortage of a market to get support and resources for discovering treatments for it. How many people are affected by rare disease? Most rare diseases are genetic and affect throughout the person's life, although symptoms do not become immediately visible. There are various causes of rare diseases. The majority of them are directly caused a change in genes or chromosomes and are passed from one generation to the next.  Most of the rare diseases appear early in life, and about 30% of children with these diseases will die after five years of birth. There may be as many as 7,000 rare diseases. Only a few types of rare diseases are diagnosed in the United States. The Americans are living with a rare disease and are estimated at between 25-30 million. In recent years, rare-disease

  What are Checkpoint inhibitors? Checkpoint inhibitors are a group of proteins that can treat cancer potentially. Checkpoint inhibitor therapy is a form of cancer immunotherapy that targets immune checkpoint. Immune checkpoints are the immune regulators, as the name denotes itself, that regulate or control the activity of immune cells, enhancing the self-tolerance of the immune system. These inhibitors when stimulated hampers the immune response to an immunologic stimulus. Checkpoint Therapy to combat Cancer Some cancerous cells do protect themselves from getting attacked by activating the immune checkpoint targets. Once activated, they block the inhibitory checkpoints, and restore the functioning of the immune checkpoints. CTLA-4 inhibitors, PD-1 inhibitors and PD-L1 inhibitors are the checkpoint inhibitors that are used to treat cancers. PD-1 inhibitors and PD-L1 inhibitors are a group of checkpoint inhibitors that are present on the surface of the cell. These imm

Medical Market Research Firms The industry of health care is a large and often complicated niche. Within the health care market research industry, researchers work to focus on the many career specialities, medical plans, patient types, diseases and conditions and much more.  The healthcare market is one of the quickly growing branches of economy. To be successful in this rapidly evolving, highly competitive sector, companies need high-quality, up-to-date information and insight.  What can Medical Market Research Firms proffer? Medical market research firms can provide with the expertise needed to understand the expansive and essential health care industry. Companies that specialize in medical market research can recruit and give them access to a wide range of medical professionals including doctors, nurses, patients, payers and others who can help deliver insight into the medical, pharmaceutical and health care industry through interviews, focus groups, studi

Introduction The Pharmaceuticals Industry proffers industry analysis of Pharmaceuticals market research reports to Business and Healthcare professionals. Many biotechnological and pharmaceutical companies prepare a myriad of Pharma Industry Reports on various indications. These pharma companies have a forte in preparing Market research reports that include analysis of pharma market share, pharmaceutical market size, pharma market outlook, pharmaceutical market forecast, pharma market trends, pharmaceutical market segmentation, and pharma market sales forecast. What is covered in pharmaresearch reports ? The Pharmaceutical Research Reports cover the historic and forecasted market size of a plethora of indications in 7 Major Markets (7MM) that include the US, EU5 (including UK, France, Germany, Italy and Spain), Japan and China. The Pharmaceutical Research Reports are commonly used as a trusted platform by many pharma companies and firms to provide a road-map

What is Immuno-oncology ? Immuno-oncology also is known as cancer immunotherapy, describes the process of utilizing the patient's immune system to fight cancer. Immuno-oncology is the cancer treatment with therapies that stimulate or suppress the body's immune system. In the last ten years, immuno-oncology has come up as an exciting approach to cancer treatment due to its specificity, adaptability and durability. One of the main areas within this field is a new class of proteins called immune checkpoints, such as PD-1, which could enable cancer cells to hide from the immune system by modulating T cell signalling.  Several distinct modalities of Immuno-oncology therapy exist, including bispecific T-cell engaging monoclonal antibodies, cellular immunotherapy and adoptive cellular therapy, cancer vaccines, checkpoint modulating monoclonal antibodies, and oncolytic viruses.  The immuno-oncology market is expected to reach USD 6 billion by 2024 from USD 3 bi

Marketing intelligence Keeping a track on the market scenario is important for all the businesses to prosper. Understanding the knowledge of the market, complete analysis of the market including prevailing trends and upcoming scenario boosts the confidence before starting any new operation. The activity of studying the market trends comprehensively is referred to as "market intelligence." The practise is so tedious and time-taking that companies have started to hire Consulting firms to perform Market intelligence for them. Consulting companies have swept the all the industries by a storm. No industry has been left untouched, including Pharma and healthcare industry. Increasing demand for better healthcare services and complex nature of the surveys conducted to study the different indications has led to a need for advanced and innovative solutions for better market analysis.   Different companies working in the Life sciences vertical require different mode

Overview Hepatitis is the inflammation of the liver. The condition can be limited to self or can advance to scarring, cirrhosis or liver cancer. Hepatitis viruses are the most common origin of Hepatitis in all over the world. Sometimes, other infections, toxic substances (e.g. alcohol, certain drugs), and autoimmune diseases can also cause Hepatitis.  “Nearly 1 million people die every year worldwide due to Hepatitis” Hepatitis types Hepatitis classification is based on the two types. One is acute if the condition lasts for less than six months and chronic when the condition persists for more than six months. Based on disease type, the hepatitis therapeutics market is segmented into A, B, C, and others. The other segment covers the hepatitis market that estimates for hepatitis D and E, which occur rarely compared to the other three conditions.  The access to hepatitis treatments of this disease has been limited to people who have a high-income level owing to

The most common form of primary liver cancer, Hepatocellular Carcinoma (HCC) is a malignant tumour of hepatocytes. Increasing Hepatocellular Carcinoma (HCC) Incidence Hepatocellular Carcinoma incidence is growing worldwide because of the dissemination of Hepatitis B and C virus infection making it the fifth most common cause of cancer.  Hepatocellular cell carcinoma is found to be more common in males as compared to females.  Moreover, 70%–90% of HCC patients have a previous history of chronic liver disease and cirrhosis. This indicates their chances of being diagnosed with chronic infection with hepatitis B virus (HBV), hepatitis C virus (HCV), alcoholic liver disease, and non-alcoholic steatohepatitis (NASH). According to DelveInsight, a healthcare business consulting firm, the total HCC incident cases in G8 countries estimated to be around 4,58,170 in 2016.   On the other hand, the total Diagnosed Advanced Hepatocellular Carcinoma cases in G8 countries aroun

Inherent qualities of immune system  The immune system of the body is primarily employed to protect the body and build a strong defence against various sorts of infections and chronic diseases.  Workhorses of the Immune system forms the backbone of the CAR-T gene therapy    Comprising of billions of cells including, the Lymphatic system consists of bone marrow, spleen, thymus and lymph nodes. Bone marrow produces the T-lymphocytes (T-Cells), which mature in thymus and are stored in spleen. T-cells which help B-lymphocytes in antibody forming, travel throughout the body to fight infection and kill cancerous cells in the body. The whole essence of the CAR-T cell therapy is based on the property of the T-cells to defend the immune system.  CAR-T cell therapy involves the venepuncture to get the samples of the T cells. These T-cells then are genetically engineered to produce receptors on their surface called chimeric antigen receptors, or CARs. CAR-T gene therapy to the