Alopecia Areata Market
Alopecia Areata is an autoimmune skin disease. The hair loss occurs on
the scalp, face, and on other areas of the body. The person's immune system
affects hair follicles that results in seizing of the hair growth stage. Genetic predisposition and environmental
factors increase the chances of developing Alopecia Areata.
Alopecia areata prevalence is estimated to be 0.1–0.2%. The development
of alopecia areata risk is evaluated to be 1.7%. All races are affected
equally, and no increase in alopecia areata prevalence has been found in a
particular ethnic group.
Presently, there is no cure and no FDA-approved Alopecia Areata
treatments for alopecia. The Alopecia Areata market is entirely influenced by
off-label drug therapies.
Based on the degree of hair loss and age, there are a variety of
Alopecia Areata treatment options available. The main goal of Alopecia Areata
treatment is to block the immune system attack or trigger the hair regrowth.
The standard Alopecia Areata treatment includes immunomodulators,
corticosteroids, and vasodilators that are available as oral and systemic
formulations. Steroids and immunotherapy are the current leading Alopecia
Areata treatments, even if they do not always guarantee regrowth and
remissions. Based on the line of therapy, Alopecia Areata therapeutic drugs are
categorized as:
First-line therapies such as intralesional corticosteroids, topical
corticosteroids, minoxidil, anthralin, topical immunotherapy, prostaglandin
analogues, topical retinoids, bexarotene, and capsaicin. Second-line therapies
such as sulfasalazine, photochemotherapy, excimer laser, and fractional photo
thermolysis laser. Third-line therapies such as systemic corticosteroids,
methotrexate, cyclosporine, azathioprine, and biologics, such as adalimumab,
alefacept, and etanercept are used in Alopecia Areata.
There are other types of treatments that are also used to manage
alopecia areata, such as platelet-rich plasma patches, which has both
proliferation-inducing as well as anti-inflammatory effects and stem cell
therapies, such as mesoderm-derived stem cells are a potential option in
alopecia areata treatment.
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