Kritika Rehani

Nonalcoholic Steatohepatitis (NASH) is the gradual form of liver injury, which carries a risk of progressive fibrosis, cirrhosis, and end-stage liver disease. It is a progressive form of non-alcoholic fatty liver disease (NAFLD) that is caused by the fat buildup in the liver. So, when this buildup leads to inflammation and damage, then it is called NASH. The disease leads to liver scarring; it is a life-threatening condition known as cirrhosis. NASH Market NASH falls under the category of silent diseases that has very few or no symptoms typically because it does not cause any symptoms until it is too late. In the early period, patients did not complain about anything specific. Even with the advancing fibrosis, the disease may not have any specific problems. However, in the later stages, patients may start developing some non-specific symptoms. The classification of fibrosis stages of NASH is as follows: No Fibrosis (F0) NASH Fibrosis (F1–F3) NASH Cirrhosis (F4). 

Epilepsy is a brain disorder that range from severe, life-threatening and disabling, to ones that are much more benign. In Epilepsy, the regular pattern of neuronal activity becomes disturbed, causing strange sensations, emotions, and behaviour or occasionally convulsions, muscle spasms, and loss of consciousness. The cause is the abnormality in brain wiring, an imbalance of nerve signalling chemicals known as neurotransmitters, which changes the essential features of brain cells called channels, or a combination of these and other factors. Epilepsy Market Many companies are involved in the launch of potential therapies that may increase Epilepsy market size in the coming years. The key players such as Marinus Pharmaceuticals, Sage Therapeutics, SK Biopharmaceuticals, UCB, Neurelis, Zogenix, Aquestive Therapeutics, INSYS Therapeutics, Engage Therapeutics, Zynerba Pharma, and many others have the potential to create a significant positive shift in the Epilepsy Market Size. 

Parkinson's Disease Market Parkinson’s Disease is a debilitating disease that is caused by degeneration of nerve cells in the brain known as the substantia nigra that controls movement.  The present Parkinson’s disease treatment options that are given to the patients include medication, complementary and supportive therapies (such as diet, exercise, physical therapy, occupational therapy, and speech therapy), and surgery. The approved medication therapies are categorized into seven groups that include Levodopa, Carbidopa-levodopa infusion (Duodopa), Dopamine agonists (Mirapex, Requip, Neupro), MAO B inhibitors (Zelapar, Azilect, Xadago), Catechol O-methyltransferase (COMT) inhibitors (Tasmar, Comtan), Anticholinergics (Cogentin, Artane), and Amantadine.   The treatment with monoamine oxidase-B (MAO-B) inhibitors, amantadine (Symmetrel), or anticholinergics may modestly improve mild symptoms; however, most patients need levodopa or a dopamine agonist. The most freque

HR-positive/HER2-negative breast cancer is the most prevalent form of breast cancer disease. This type reports having a higher percentage among all breast cancers.  HR positive/ HER2 negative breast cancer market Hormone receptors (HR) are the proteins, which receive hormone signals and command the cancer cells to proliferate. If the breast cancer cells receive signals from the hormone estrogen that could promote tumour growth, then it is called as estrogen receptor-positive (ER+) breast cancer. If cancerous cells receive the signals from the hormone progesterone that could spur the growth, it is called progesterone receptor-positive (PR+) breast cancer. Also, human epidermal growth factor receptor 2 (HER2) is a gene that aids in controlling how cells grow, divide, and repair themselves.   Many women have breast cancer globally; the prevalence is increasing every day. DelveInsight has reported that the total Breast Cancer incident population in the 7MM is expected to gro

What is Sickle Cell Disease? Sickle Cell Disease market Sickle Cell disease, which is also known as sickle cell anaemia. It includes a group of disorders that affect the red blood cells.Sickle Cell disease is an inherited blood disorder that is distinguished by defective haemoglobin. The changes in which red blood cells behave differently are dehydration, low oxygen levels and elevated temperature, which may cause the red blood cells to block the small blood vessels, restricting blood flow.   How much population is affected by Sickle Cell Disease? Sickle cell disease is irreversible that affects males and females equally, and is responsible for increased morbidity and mortality in affected persons. Sickle Cell Disease prevalance There were approximately 133,385 Sickle Cell Disease prevalent cases in 2017 in the 6MM. As per DelveInsight , the United States reports for the highest Sickle Cell Disease prevalent population due to a large number of immigrants from A