Angioimmunblastic T-Cell Lymphoma (ATCL) Market Insights, Market Forecast Report 2030

 Angioimmunoblastic T-cell lymphoma (AITL) is a rare form of non-Hodgkin lymphoma, which is a group of related malignancies (cancers) that affect the lymphatic system (lymphomas).

DelveInsight's "Angioimmunoblastic T-Cell Lymphoma Market Report 2030 delivers an in-depth understanding of the Angioimmunoblastic T-Cell Lymphoma, historical and forecasted epidemiology as well as the Angioimmunoblastic T-Cell Lymphoma market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.

The Angioimmunoblastic T-Cell Lymphoma market report provides current treatment practices, emerging drugs, Angioimmunoblastic T-Cell Lymphoma market share of the individual therapies, current and forecasted Angioimmunoblastic T-Cell Lymphoma market Size from 2017 to 2030 segmented by seven major markets. The Report also covers current Angioimmunoblastic T-Cell Lymphoma treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assesses the underlying potential of the market.

Geographies Covered in the report:

• The United States

• EU5 (Germany, France, Italy, Spain, and the United Kingdom)

• Japan

Study Period: 2017-2030

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Angioimmunoblastic T-Cell Lymphoma Disease Understanding and Treatment Algorithm

AITL is characterized by the transformation of a T-cell into a malignant cell. Abnormal, uncontrolled growth and multiplication (proliferation) of malignant T-cells may lead to enlargement of a specific lymph node region or regions; involvement of other lymphatic tissues, such as the spleen and bone marrow; and spread to other bodily tissues and organs. A key and differentiating aspect of AITL is dysfunction of the immune system, which can lead to a variety of symptoms.

The DelveInsight Angioimmunoblastic T-Cell Lymphoma market report gives a thorough understanding of the Angioimmunoblastic T-Cell Lymphoma by including details such as disease definition, symptoms, causes, pathophysiology, diagnosis and treatment.

Angioimmunoblastic T-Cell Lymphoma Epidemiology 

AITL is a rare form of NHL and usually presents in the late stage due to the atypical laboratory findings. Immunohistochemistry of the lymph node in AITL is characterized by positive CD2, CD3, CD4, CD10, CXCL‐13, PD1 often BCL‐6 and CD20 positive. According to the 2016 revision of the World Health Organization classification of lymphoid neoplasms, AITL now resides under the umbrella category of nodal T cell lymphomas with T follicular helper (TFH) phenotype.

The Angioimmunoblastic T-Cell Lymphoma epidemiology division provide insights about historical and current Angioimmunoblastic T-Cell Lymphoma patient pool and forecasted trend for every seven major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the DelveInsight report also provides the diagnosed patient pool and their trends along with assumptions undertaken. 

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Angioimmunoblastic T-Cell Lymphoma Drug Chapters

The dynamics of the Angioimmunoblastic T-cell Lymphoma (AITL) market is anticipated to change in the coming years owing to the improvement in the rise in the number of healthcare spending across the world. Key players, such as Celgene, Verastem, Beigene, Merck, Solasia Pharma, Kura Oncology and others are involved in developing drugs for Angioimmunoblastic T-cell Lymphoma (AITL).

Drug chapter segment of the Angioimmunoblastic T-Cell Lymphoma report encloses the detailed analysis of Angioimmunoblastic T-Cell Lymphoma marketed drugs and late stage (Phase-III and Phase-II) pipeline drugs. It also helps to understand the Angioimmunoblastic T-Cell Lymphoma clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug and the latest news and press releases.

Angioimmunoblastic T-Cell Lymphoma Market Outlook

Patients with AITL, one of the most common types of PTCL, typically present with advanced disease, systemic symptoms, and immune deregulation. Treatment can be challenging owing to frequent relapses after initial and subsequent therapy. 

The choice of front-line treatment depends on the goal of therapy. For most patients with AITL, the initial goal of treatment is curative; therefore, an aggressive approach with combination chemotherapy followed often by consolidation with autologous stem-cell transplant (ASCT) is used. For elderly patients, or those with significant comorbidities, milder therapy (such as corticosteroids with or without low-dose chemotherapy) may be appropriate.

Although this approach is not curative, it does provide the potential for prolonged disease control and maintenance of quality of life.

Options in this scenario include intermittent courses of single-agent prednisone, combination chemotherapy (such as low-dose cyclophosphamide and etoposide combined with prednisone) or single-agent chemotherapy (Romidepsin, Belinostat, Pralatrexate, Bendamustine, Brentuximab vedotin, Cyclosporine A, Lenalidomide, Gemcitabine and others) or relapsed or refractory disease. These treatments can often suppress the symptoms that accompany AITL; typically, however, ongoing therapy is required at some frequency for maintenance of disease control.

The Angioimmunoblastic T-Cell Lymphoma market outlook of the report helps to build the detailed comprehension of the historic, current, and forecasted Angioimmunoblastic T-Cell Lymphoma market trends by analyzing the impact of current therapies on the market, unmet needs, drivers and barriers and demand of better technology.

According to DelveInsight, Angioimmunoblastic T-Cell Lymphoma market in 7MM is expected to change in the study period 2017-2030.

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